Dr. Keith Lau

On July 1, 2003, Dr. Keith Lau began his first year of training in pediatric nephrology at the UTHSC. Dr. Lau graduated from medical school in Hong Kong and completed his pediatric residency training at the University of Tennessee, Chattanooga. The second and third year of his fellowship consists of basic research training in the laboratory of Dr. Hiroko Nishimura. During his first two years of fellowship training Dr. Lau has been extremely productive with respect to publications that include first author on two case series, one review article and several case reports. He has presented first author work the annual meetings of the Pediatric Academic Societies (2004 and 2005), the American Society of Nephrology (2004 and 2005), and the Federation of Societies of Experimental Biology (2005). He has obtained competitive local funding from the Le Bonheur Children’s Medical Center ($10,000 in 2004 and the $15,000 Accredo scholar award in 2005) and the National Kidney Foundation of West Tennessee to support his research in Dr. Nishimura’s laboratory. The following publications and presentations have resulted from Dr. Lau’s fellowship training to date:

Publications

Lau KK, Gaber LW, Delos Santos NM, Fisher KA, Grimes SJ, Wyatt RJ: Pediatric IgA nephropathy: clinical features at presentation and outcome for African-Americans and Caucasians. Clinical Nephrology 62: 167-172, 2004

Lau KK, Kink RJ, Jones: Myoclonus associated with intraperitoneal imipenem. Pediatric Nephrology 19: 700-701, 2004

Lau KK, Gaber LW, Delos Santos NM and Wyatt RJ: C1q nephropathy: Features at presentation and outcome. Pediatric Nephrology 20: 744-749, 2005

Lau KK and Wyatt RJ: Glomerulonephritis. Adolescent Medicine Clinics 16: 67-85, 2005

Lau KK, Weiss AR, Jones DP: Polyuria associated with high-dose methotrexate in two patients with acute lymphoblastic leukaemia. Journal of Oncology Pharmacy Practice 11: 31-33, 2005

Lau KK, Ault BH, Jones DP: Polymicrobial peritonitis including Pantoea agglomerans from teething on a catheter. Southern Medical Journal 98: 580-581, 2005

Lau KK, Delos Santos NM: Post-infectious acute glomerulonephritis with predominant mesangial deposition of IgA. Clinical and Experimental Nephrology 9: 262-263, 2005

Lau KK, Wyatt RJ, Gaber LW: Biopsy Teaching Case: Purpura followed by proteinuria in a 7 year old girl. American Journal of Kidney Diseases 46: 1140-1144, 2005

Lau KK, Escue EJ, Ault BH, Jones DP, Storgion SA: Argatroban in post-cardiovascular surgery patient with heparin-induced thrombocytopenia requiring hemodialysis and continuous hemofiltration. Journal of Pharmacy Technology 21: 213-216

Lau KK, Ault BH: Teaching case: A child with recurrent episodes of dark urine: question. Pediatric Nephrology 21: 271, 2005

Lau KK, Ault BH: Teaching case: A child with recurrent episodes of dark urine: answer. Pediatric Nephrology 21: 272-274. 2005

Lau KK, Delos Santos NM: Pediatric C1q nephropathy and incidental proteinuria (letter). Pediatric Nephrology 21: 883, 2006

Lau KK, Jones DP, Hastings MC, Gaber LW, Ault BH: Short term outcomes of severe lupus nephritis in a cohort of predominately African-American children. Pediatric Nephrology 21: 655-662, 2006

Lau KK, Delos Santos NM, Hastings MC, Ault BH, Jones DP, Roy III S, Ault BH, Wyatt RJ: Tularemia infection in a pediatric patient with chronic renal insufficiency and inguinal lymphadenopathy. Infectious Diseases in Clinical Practice 14: 248-256

Lau KK, Hastings MC, Arnold SL, Jones DP, Boulden T, Shokouh-Amiri H, Wyatt RJ, Ault BH: Bartonella infection presenting With prolonged fever in a pediatric renal transplant recipient. The Internet Journal of Infectious Diseases 5: 1

Hastings MC, Wyatt RJ, Jones DP, Lau KK, Powell SL, Hayes DW, Gaber LW, Gaber AO, Ault BH: Five years' experience with Thymoglobulin induction in a pediatric renal transplant population. Pediatric Transplantation 10: 805-810, 2006

Hastings MC, Wyatt RJ, Ault BH, Jones DP, Lau KK, Gaber AO, Gaber LW: Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsy. Pediatric Nephrology 22: 742-746, 2007

Moldoveanu Z, Wyatt RJ, Lee J, Tomana M, Julian BA, Mestecky J, Huang W-Q, Anreddy SR, Hall S, Hastings MC, Lau KK, Cook WJ, Novak J: Elevated serum levels of galactose-deficient IgA in patients with IgA nephropathy. Kidney International 71: 1148-1154, 2007

Lau K, Jones D, Gaber O, Nezakatgoo N: Use of a “composite” vascular access graft in a young child on hemodialysis. Hemodialysis International 11: 190-192, 2007

Nishimura H, Yang Y, Lau K, Kuykindoll RJ, Fan Z, Yamaguchi K, Yamamoto T: Aquaporin-2 water channel in developing quail kidney: possible role in programming adult homeostasis. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 293: R2147-R2158, 2007

Lau KK, Yang Y, Cook GA, Wyatt RJ, Nishimura H: Control of aquaporin 2 expression in collecting ducts of quail kidneys. General and Comparative Endocrinology 160: 288-294, 2009

Presentations

Lau KK, Gaber LW, Wyatt RJ: Clinico-pathological features and outcomes of C1q nephropathy in a single pediatric center. American Society of Nephrology, 2004 (poster)

Lau KK, Gaber LW, Delos Santos NM, Fisher KA, Grimes SJ and Wyatt RJ: Comparison of IgA nephropathy (IgAN) in Caucasians (Cau) and African-Americans (AA) diagnosed since 1990. Pediatric Academic Societies/American Society of Pediatric Nephrology, 2004 (poster)

Lau K, Yang Y, Thomason D, Wyatt R, Nishimura H: Differential increase in the mammalian type nephrons in avian kidney. Federation of Societies of Experimental Biology, 2005 (poster)

Lau KK, Gaber LW, Pleming CR, Jones DP, Ault BH: Clinical features and short term outcomes of severe lupus nephritis (LN) in a pediatric center with predominantly African-American (AA) patients (pts). Pediatric Academic Societies/American Society of Pediatric Nephrology, 2005 (poster)

Lau KK, Yang Y, Wyatt RJ, Nishimura H: Characterization of the functions of the aquaporin system in quail kidneys. American Society of Nephrology, 2005 (poster)

Lau K, Yang Y, Cook G, Wyatt R, Nishimura H: Hormonal control of aquaporin 2 requires advanced tubular structures in avian kidneys. Southern Society of Clinical Investigation (SSCI) Nephrology Young Investigators' Forum (platform), March 2, 2006 and the Southern Society for Pediatric Research, March 5, 2006 (platform), Atlanta, GA. Dr. Lau received a travel grant from the SSCI to attend both meetings.

Lau K, Yang Y, Cook G, Wyatt R, Nishimura H: Differential control by ADH of looped and loopless nephrons in quail kidneys. Federation of Societies of Experimental Biology Meeting, 2006 (poster)

Lau K, Moldoveanu Z, Wyatt R, Huang WQ, Tomana M, Mestecky J, Lee J, Julian B, Novak J: Elevated serum concentration of Helix aspersa lectin-binding IgA1 (HAA-IgA1) in pediatric patients (pts) with HSP nephritis (HSPN). Platform presentation at the annual Pediatric Academic Societies/American Society of Pediatric Nephrology, 2006 (platform)

Present position

Dr. Lau is an Assistant Professor of Pediatrics at the University of California Davis.