JENA J. STEINLE, Ph.D.

Assistant Professor

Department of Ophthalmology

Department of Anatomy and Neurobiology

Hamilton Eye Institute

The University of Tennessee College of Medicine

Address

The University of Tennessee Health Science Center

930 Madison Ave, Suite 722A

Memphis, TN 38163

Tel: (901) 448-1910; Fax: (901) 448-5028;

Education

Ph.D. Institution: University of Kansas Medical Center, Kansas City, KS

Postdoctoral: Texas A&M University Health Science Center, Temple, TX

Research Interests

Research in our lab investigates changes in the choroid and retina in age-related macular degeneration and diabetic retinopathy. We are currently working on the effects of loss in sympathetic innervation (the fight or flight system) on the retinal pathology associated with diabetic retinopathy and choroidal pathology with macular degeneration. We use modern cellular and molecular biology techniques on cell culture and animal samples to evaulate the mechanisms for the disease processes. We are also interested in the interactions between sympathetic nerves and the vasculature they innervate.

Recent Publications

• Steinle JJ, Cappocia FC Jr, Jiang Y. Beta-adrenergic receptor regulation of growth factor protein levels in human choroidal endothelial cells. Growth Factors. 2008 Nov 19;:1 [Epub ahead of print] PMID: 19021032
• Steinle JJ, Chin VC, Williams KP, Panjala SR. Beta-adrenergic receptor stimulation modulates iNOS protein levels through p38 and ERK1/2 signaling in human retinal endothelial cells. Exp Eye Res. 2008 Jul;87(1):30-4. Epub 2008 Apr 26. PMID: 18541234
• Steinle JJ, Sharma S, Chin VC. Normal aging involves altered expression of growth factors in the rat choroid. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):135-40. PMID: 18314447
• Walker RJ, Steinle JJ. Role of beta-adrenergic receptors in inflammatory marker expression in Müller cells. Invest Ophthalmol Vis Sci. 2007 Nov;48(11):5276-81. PMID: 17962483
• Smith CP, Steinle JJ. Changes in growth factor expression in normal aging of the rat retina. Exp Eye Res. 2007 Dec;85(6):817-24. Epub 2007 Aug 29. PMID: 17936752
• Smith CP, Sharma S, Steinle JJ. Age-related changes in sympathetic neurotransmission in rat retina and choroid. Exp Eye Res. 2007 Jan;84(1):75-81. Epub 2006 Oct 30. PMID: 17074321

view complete list of references (pubmed link)