|
| |
EDWARD CHAUM, M.D., Ph.D.
- Plough Foundation Professor of Retinal Diseases
Associate Professor
- Department of Ophthalmology
- Department of Pediatrics
- Department of Anatomy and Neurobiology
- The University of Tennessee College of Medicine
Address
- The University of Tennessee Health Science Center
- Hamilton Eye Institute
- 930 Madison Avenue, Suite 731
- Memphis, TN 38163
- Tel: (901) 448-5975;
Education
- Ph.D. Institution: Department of Cell Biology and Genetics, Cornell Graduate School of Medical Sciences
- M.D. Institution: Cornell University Medical College
Research Interests
The focus of the basic science research program in our laboratory is in five major areas:
- Translational research in the development and application of gene therapy to the treatment of retina degenerative diseases,
- Tissue engineering approaches to understanding and modulating the growth, aging and wound healing responses of ocular retinal pigment epithelial cells (RPE),
- Molecular analyses of retinal pigment epithelial cell responses to oxidative stress,
- Characterization of a newly discovered IGF binding protein regulatory system in the RPE, and
- Tele-ophthalmology and automated diagnostics
Other areas of active research include collaborations on numerous pilot basic science and clinical projects with investigations into:
- Genomic analysis of RPE gene expression,
- The role of CD81 in proliferative vitreoretinopathy, wound healing and retinal detachment,
- The role of Arf gene mutations in the developmental eye anomaly persistent fetal vasculature,
- Electrochemical quantification of blood metabolites and drugs, and
- Nanotechnology applications in retinal surgery, and
- Clinical research studies.
Links
- Ophthalmology - Edward Chaum
Recent Publications
- Chaum E, Karnowski TP, Govindasamy VP, Abdelrahman M, Tobin KW.
Automated diagnosis of retinopathy by content-based image retrieval.
Retina. 2008 Nov-Dec;28(10):1463-77.
PMID: 18997609
- Tobin KW, Chaum E, Govindasamy VP, Karnowski TP.
Detection of anatomic structures in human retinal imagery.
IEEE Trans Med Imaging. 2007 Dec;26(12):1729-39.
PMID: 18092741
- Tobin KW, Abdelrahman M, Chaum E, Govindasamy V, Karnowski TP.
A probabilistic framework for content-based diagnosis of retinal disease.
Conf Proc IEEE Eng Med Biol Soc. 2007;2007:6744-7.
PMID: 18003575
- Karnowski TP, Govindasamy VP, Tobin KW Jr, Chaum E.
Locating the optic nerve in retinal images: comparing model-based and Bayesian
decision methods.
Conf Proc IEEE Eng Med Biol Soc. 2006;1:4436-9.
PMID: 17945838
- Yang H, Yang X, Lang JC, Chaum E.
Tissue culture methods can strongly induce immediate early gene expression in
retinal pigment epithelial cells.
J Cell Biochem. 2006 Aug 15;98(6):1560-9.
PMID: 16552722
- Chaum E, Fawzi A, Chang TS, Shah GK.
Diagnostic and therapeutic challenges.
Retina. 2006 Feb;26(2):219-22. No abstract available.
PMID: 16467682
view complete list of references (pubmed link)
|
|
|
