Integrated Program in Biomedical Sciences

Genetics, Functional Genomics, and Proteomics

Ron Adkins, Ph.D., Assistant Professor, Dept. of Pediatrics, radkins@uthsc.edu

Secondary Appointments:
Laboratory Location: 308 West Patient Tower, Le Bonheur Children’s Hospital

Identification of genetic polymorphisms that underlie susceptibility to fetal growth restriction and preeclampsia.

Cheng Cheng, Ph.D., Adjunct Assistant Professor, Dept. of Biostatistics, cheng.cheng@stjude.org

Secondary Appointment: Cancer and Developmental Biology
Lab Location: Room R6028 B-L Building, St. Jude

Statistical analysis methodologies for data analyses in cell and molecular biology and genetics, particularly in genome-wide studies and genotype-phenotype association studies.

Terrance Cooper, Ph.D., Van Vleet Professor, Dept. of Molecular Sciences, tcooper@uthsc.edu

Secondary Appointments: Cell Biology and Biochemistry
Laboratory Location: 516 Molecular Sciences Building

Eukaryotic genome-wide transcription regulatory networks and cell biology of transcriptional regulation.

Yan Cui, Ph.D., Assistant Professor, Dept. of Molecular Sciences, ycui2@uthsc.edu

Secondary Appointments:
Laboratory Location: 101A Molecular Sciences Building

Computational methods for microarray data analysis and gene network modeling.

Dominic Desiderio, Ph.D., Professor, Dept. of Neurology, ddesiderio@uthsc.edu

Secondary Appointments: Neuroscience
Laboratory Location: 117 Johnson Building

The use of proteomics and peptidomics to study human pathology; Mass spectrometric analysis of neuropeptides.

Weikuan Gu, Ph.D. Associate Professor, Dept. of Orthopaedic Surgery, wgu@uthsc.edu

Secondary Appointments: Molecular, Cellular, and Systems Physiology
Laboratory Location: E340 Coleman Building and BECEG 12, 13 Veterans Affairs Medical Center

Positional cloning and functional study of spontaneous mutations in mice; Identification of genetic factors that regulate bone quality and resistance to arthritis.

Martha Howe, Ph.D., Van Vleet Professor, Dept. of Molecular Sciences, mhowe@uthsc.edu

Secondary Appointments: Microbial Pathogenesis, Immunology and Inflammation
Laboratory Location: 711 Molecular Sciences Building

Mechanism of transcription activation by the bacteriophage Mu Mor/C family of transcription activators.

Clayton Naeve, Ph.D., Member, Dept. of Molecular Biotechnology, clayton.naeve@stjude.org

Secondary Appointments:
Laboratory Location: D1007D, Mail Stop 312 Danny Thomas Research Tower, St. Jude

Development and application of bioinformatics and biotechnology methodology.

David Nelson, Ph.D., Associate Professor, Dept. of Molecular Sciences, dnelson@uthsc.edu

Secondary Appointments: Cell Biology and Biochemistry
Laboratory Location: 101C, 101D Molecular Sciences Building

Bioinformatics and evolution of the cytochrome P450 superfamily; Molecular history of eukaryotic life.

Lawrence Reiter, Ph.D., Assistant Professor, Department of Neurology, lreiter@uthsc.edu

Secondary Appointment: Neuroscience
Laboratory Location: 431 Johnson Building

Neurogenetics of autism with an emphasis on the genes involved in synaptic plasticity using Drosophilia and mouse models.

Mary Relling, Pharm.D., Member, Dept. of Pharamaceutical Sciences, mary.relling@stjude.org

Secondary Appointments: Molecular Therapeutics and Cell Signaling
Laboratory Location: D1052 Danny Thomas Research Tower, St. Jude

Pharmacogenetics of antileukemic agents; Drug-induced cancers.

Charles Rock, Ph.D., Member, Dept. of Infectious Disease, charles.rock@stjude.org

Secondary Appointments:
Laboratory Location: 8050 Integrated Research Center, St. Jude

Control points in fatty acid biosynthesis; Regulation of membrane phospholipid metabolism; Small molecule therapeutics.

Kazuko Sakata, Ph.D., Assistant Professor, Department of Pharmocology, ksakata@uthsc.edu

 Secondary Appointment:  Molecular Cellular and Systems Physiology
             Laboratory Location: 418 Crowe Research Bldg.

Current projects focus on studying the roles of activity-dependent expression of
BONF (Brain Derived Neurotrophic Factor) in depression and anxiety, using molecular
and biochemical, electrophysiologyical, and behavioral techniques with genetically modified mice.

Erin Schuetz, Ph.D., Member, Dept. of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, erin.schuetz@stjude.org

Secondary Appointment:  Molecular Therapeutics, Drug Development and Cell Signaling
            Laboratory Location: Room I5204 Chili Care Center, St. Jude

Gene therapy for hematopioetic disorders; Biology of  hematopioetic stem cells and ABC transporters.

Robert Williams, Ph.D., Professor, Dept. of Anatomy and Neurobiology, rwilliams@nb.uthsc.edu

Secondary Appointments:
Laboratory Location: 501 Wittenborg Building

Genomic analysis of disease susceptibility and individual differences, with a special emphasis on the brain, eye, and visual system.

Revised 18 August 2008