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College
of Graduate Health SciencesIntegrated Program in Biomedical Sciences |
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Cancer and Developmental Biology TrackSuzanne Baker, Ph.D., Associate Member, Dept. of Developmental Neurobiology, suzanne.baker@stjude.org Secondary Appointment: Cell Biology and Biochemistry Normal and neoplastic growth regulation in the brain. Mustafa Dabbous, Ph.D., Professor, Dept.of Molecular Sciences, mdabbous@uthsc.edu Secondary Appointment:
Secondary Appointment: Genetics, Functional Genomics and Proteomics Understanding the molecular mechanisms that regulate normal hematopoiesis and determining how these pathways are altered in human leukemia.
Secondary Appointment: Cell Biology and Biochemistry Structural studies of tumor suppressor proteins.
Secondary Appointment: Genetics, Functional Genomics and Proteomics Jill Lahti, Ph.D. Associate Member, Dept. Genetics and Tumor Cell Biology, jill.lahti@stjude.org Secondary Appointment: Cell Biology and Biochemistry The role of caspases and apoptosis in tumorigenesis, the function of CDK proteins in transcription and splicing, and the regulation of mitosis by DNA helicases and CDKs.
Lab Location: 405, 411 Crowe Building Development of novel antitumor agents, PKC-mediated apoptotic signalling, circumvention of cellular drug resistance, development of dual antitumor/cardioprotective compounds.
Secondary Appointment: Molecular Therapeutics and Cell Signaling Prostate cancer, novel apoptosis-inducing genes, viral-based gene therapy and breast cancer, tumor angiogenesis and metastasis.
Secondary Appointment: Neuroscience
Secondary Appointment:
Secondary Appointment: Neuroscience Oral cancer, gene profiling, microarray, rodent cancer models, cancer stem cells, taste neurobiology, neurotrophic factors, transgenic technology, adult stem cells, dental pulp, tooth.
Secondary Appointment: Genetics, Functional Genomics and Proteomics Role of homeobox genes in early mammalian development
Regulation of anti-apoptotic MCL-1 during hematopoietic development and function.
Secondary Appointment: Cell Biology and Biochemistry Interferons and cytokines: receptor structure, transmembrane signaling, regulation of gene expression and mechanism of anticancer action.
Secondary Appointment: Cell Biology and Biochemistry
Secondary appointment: Cell Biology and Biochemistry Breast cancer, metastasis, hypoxia-induced gene expression and transgenic animal models; identification of the von Hippel-Lindau-(VHL)-regulated proteome.
Secondary Appointment: Molecular, Cellular, and Systems Physiology
Secondary Appointment: Genetics, Functional Genomics and Proteomics
Secondary Appointment: Molecular Therapeutics and Cell Signaling Regulation of mammalian DNA topoisomerase IIa gene expression and the role of topo IIa in G2/M cell cycle arrest.
Secondary Appointment: Molecular Therapeutics and Cell Signaling Preclinical development of novel antitumor agents
Secondary Appointment: Molecular Therapeutics and Cell Signaling. Zhaohui Wu,M.D.,Ph.D., Assistant Professor, Dept. of Pathology and Laboratory Medicine, zwu6@uthsc.edu Secondary Appointment: Cell Biology and Biochemistry DNA damage responses and gene transcription: NF-kB signaling, genotoxic stress signal transduction, apoptosis and gene regulation in cancer development.
Secondary Appointment: Cell Biology and Biochemistry Characterization of the p53 tumor suppressor signaling pathway.
Secondary Appointment: Cell Biology and Biochemistry Role of cell adhesion molecule integrin and integrin-associated tetraspanin in cell migration, vascular morphogenesis, and cancer metastasis Revised 18 August 2008
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