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Marion Dugdale, M.D.
Position
Professor of Medicine/Hematology; Director, Hemophilia Clinic
Education / Training
- Bryn Mawr College - B.A. (Magna Cum Laude); 1947-1950
- Harvard Medical School - M.D. (Alpha Omega Alpha); 1950-1954
- Internship and Residency: University of North Carolina Memorial Hospital, Chapel Hill, NC; 1954-1957
- Assistant Resident in Pathology (Coagulation), University of North Carolina Medical School, Chapel Hill, North Carolina; 1958
- Fellowship in Hematology, American Cancer Society, Duke Hospital, Durham, NC; 1957-1958
- Resident in Medicine-Hematology, Department of Medical Labs, UT Memphis; 1958-1959
- Research Fellow in Hematology, UT Memphis; Oct. 1959-Sept. 1962
Professional Positions
- Instructor in Medicine, Division of Hematology, University of Tennessee, Memphis; 1962-1963
- Assistant Professor of Medicine, Division of Hematology, University of Tennessee; 1963-1968
- Associate Professor of Medicine, Division of Hematology, University of Tennessee; 1968-1973
- Director, UT Hemophilia Clinic, Van Vleet Cancer Center, University of Tennessee; 1972-Present
- Professor of Medicine, Division of Hematology, University of Tennessee; 1973-Present
- Member, Advisory Committee of the Tennessee State Hemophilia Program
Honors
- Humanitarian Award, Memphis Chapter, National Hemophilia Foundation, 1977
- Distinguished Teaching Award (Pathophysiology), 1981-1982
- Gene H. Stollerman Outstanding Faculty Teaching Award, 1981 & 1985
- President, UT/Bowld Hospital, 1986
- President, College of Medicine Faculty Organization, 1986-1987
- Award of Appreciation (Outstanding lecturer, Class of '87)
- National Hemophilia Foundation, Special Award for Commitment to the Improvement of Hemophilia Care in West Tennessee, 1987
- Distinguished Service Award, UT/Bowld Hospital, 1988
- Memphis Chapter, National Hemophilia Foundation, The Marion Dugdale Scholarship Fund, 1988
- Clinical Teaching Award, 1989
- Best Lecturer (Medical Student Executive Council), 1992
- Golden Apple Teaching Award, 1992
- Service to the Adult Hemophilia Community of Memphis, 1993
- Regional Medical Center at Memphis Distinguished Service, 1994
- National Alumni Distinguished Professor, 1997
- Alumni Distinguished Service Professor, 1999
- Member, American Society of Hematology
- Member, International Society of Thrombosis and Hemostasis
- Member, National Hemophilia Foundation
- Member, World Federation of Hemophilia
Research Support
Member of cooperative project groups:
- CDC - "Hemophilia - Natural History of Joint Disease and Liver Disease
- NIH - "Hemophilia - Liver Disease in HIV-positive Patients, Incidence of Malignancy"
Relevant Publications
- Diggs, L. W. and Dugdale, M.: Hemorrhagic and Thromboembolic Diseases. In a Textbook of Clinical Pathology. 7th Ed. Seward E. Miller, 1966.
- Dugdale, M.: Disorders of Hemostasis. In a Textbook of Clinical Pathology. 8th Ed. Seward E. Miller, Editor; Williams and Wilkins, Baltimore, 1971.
- Dugdale, M.: Clinical Use of Sex Steroids. James R. Givens Year Book Medical Publishers, Inc., 1980
- Dugdale, M.: Coagulation and Hematology during Liver Transplantation in. In, Hepatic Transplantation in Cyclosporine era: An Emphasis on Histopathology. James W. Williams. W.B. Saunders Company, Philadelphia, 1989.
- Lasslo, A., Dugdale, M., Dillingham, E.O., Gollamudi, R. and Lawrence, W.H.: Surface-Active Antithrombotic Agents for Prostheses. Cardiovascular Science & Technology: Basic & Applied, I, Oxymoron Press, 1989.
- Dugdale, M.: Anticoagulants, Antithrombotis and Thrombolytic Agents. In Biochemical Pharmacology of Blood and Bloodforming Organs. Ed. James W. Fisher Springer-Verlag, Berlin, 1992.
- Neft, L.G., Dugdale, M., Biggs, A.W., and Raines, S.L.: Treatment of Abnormal Bleeding Associated with Prostatic Disease by Intravenous Fat Emulsion. J. of Urol. 85:329-333, March, 1961.
- Diggs, L.W. and Dugdale, M.: Series of articles on "Blood Coagulation" published in consecutive issues of the Memphis and Mid-South Medical Journal and representing material presented at a workshop dealing with tests used in hemorrhagic and thrombotic diseases. 1 Blood Coagulation. 37:283, June, 1962
- Dugdale, M.: II General Principles of Hemostasis. 37:337, July, 1962.
- Dugdale, M.: VI Platelets and Platelet Function. 37:421, October, 1962.
- Dugdale, M.: VII Blood Coagulation. 37:499, December, 1962.
- Dugdale, M.: VIII Blood Coagulation. 37, January, 1963.
- Dugdale, M.: IX Fibrinolytic System. 37, February, 1963.
- Pate, J.W. and Dugdale, M.: Coagulation Studies on Blood from the Right and Left Sides of the Heart. Am. J. Surg. 107(6), June, 1964.
- Dugdale, M.: Multiple Myeloma. Filmstrip with Accompanying Booklet Presented at the Meeting of the Am. Acad. of Ortho. Surg., Film 42, 1965.
- Dugdale, M.: Myeloma Multiple. Filmstrip in Spanish for the Am. Acad. of Ortho. Surg. Meeting, 1966.
- Dugdale, M., Nofzinger, J.D., Murphey, F.: Some Effects of Low Molecular Weight Dextran on Coagulation. Thrombosis et Diathesis Haemorrhagica. XV, 1966.
- Dugdale, M. and Fort, A.T.: Busulfan Treatment of Leukemia During Pregnancy. JAMA 199: 176, 1967.
- Dugdale, M. and Masi, A.T.: Effects of Oral Contraceptives on Blood Clotting. Second Report on the Oral Contraceptives, Advisory Committee on Obstetrics and Gynecology, Washington, D.C., FDA, pp. 43-51, 1969.
- Dugdale, M.: The Platelet and Hypothermia. Blood 34: 532-533, 1969.
- Masi, A.T. and Dugdale, M.: Cerebrovascular Diseases Associated with the Use of Oral Contraceptives. Annals of IM 72(1):111-121, January 1970.
- Dugdale, M. and Masi, A.T.: Hormonal Contraception and Thromboembolic Disease: Effects of the Oral Contraceptives on Hemostatic Mechanisms. J. Chronic. Dis. 23:775-790, 1971.
- Denton, I.C., Robertson, J.T., and Dugdale, M.: Assessment of Early Platelet Activity in Experimental Subarachnoid Hemorrhage and Middle Cerebral Artery Occlusion in the Cat. Stroke 2: 268-272, 1971.)
- Salky, N., and Dugdale, M.: Platelet Abnormalities in Ischemia Heart Disease. Am. J. Cardiology 32: 612-617, 1973.
Morgan, H., Nofzinger, J.D., Robertson, J.T., and Dugdale, M.: Hemorrhagic Studies with Severe Hemodilution in Profound Hypothermia
- and Cardiac Arrest. J. Surg. Res. 14: 459-464, 1973.
- Morrison, J.C., Ellis, G., Jones, T., Wiser, W.L., Whybrew, W.D., Bucovaz, E.T., Dugdale, M., and Fish, S.A.: The Effects of Antibiotics on Serum Fibrinogen Levels. Obstetrics and Gynecology 42: 80-86, 1973.
- Dugdale, M.: Effects of the Oral Contraceptives on the Vascular System. Vol. 1: Pharmacology and the Future of Man Proceedings of the 5th Int. Congress on Pharmacology, San Francisco, 1972, pp. 260-268. S. Karger, Basel, Switzerland, 1973.
- Quintana, R.P., Dugdale, M., and Lasslo A.: Dynamics of Human Blood Platelets Membrane Integrity. Throm. Res. 16:543-550, 1979.
- White, R.P., Chapleau, C.E, Dugdale, M., and Robertson, J.T.: Cerebral Arterial Contractions Induced by Human and Bovine Thrombin. Stroke 11(4): 363-368, 1980.
- Dugdale, M.: Side Effects of Sex Steroid Therapy: Clotting and Platelet functions. Year Book Medical Publishers, Inc., 1980.
- Quintana, Ronald P., Lasslo, A., Dugdale, M. Goodin, Lisa L., and Burkhardt, Eric F.: Effects of Ethanol and of Other Factors on ADP-Induced Aggregation of Human Blood Platelets In Vitro. Thrombosis Research 20: 403-415, 1980.
- Quintana, R.P., Lasslo, A., Dugdale, M., and Goodin, L.L.: Relationships Between the Chemical Constitution of Carbamoylpeperidines and Related Compounds, and Their Inhibition of ADP-Induced Human Blood Platelet Aggregation. Thrombosis Research 22:665-680, 1981.
- Quintana, R.P., Lasslo, A., and Dugdale, M.: Human Blood Platelet Aggregation Inhibitory Target Sites Assumed to Involve Membrane Phospholipids. Biophysical Society, Volume 37, January, 1982.
- Lasslo, A., Quintana, R.P., Dugdale, M., Johnson, R.W., and Naylor, J.L.: Development of Novel Surface-Active Compounds for prophylaxis Against and Treatment of Thromboembolic Complications. American Society for Artificial Internal Organs. April-June, 1982.
- Dugdale, M. and Smith, R.M.: The Patient with Bleeding Problems. Dental Clinics of North America 27(2): 271-288, 1983.
- Lasslo, A., Quintana, R.P., Dugdale, M., Johnson, R.W., and Naylor, J.L.: Development of Novel Surface-Active Compounds for Prophylaxis Against and Treatment of Thromboembolic Complications. ASAIO, 6(2):47-59, 1983.
- Lasslo, A, Quintana, R.P., Johnson, Randy W., Naylor, Jen L., and Dugdale, M.: Relationships between the chemical constitution of aggregation inhibitors and human blood platelet response profile. Biochimica et Biophysica Acta, 772:84-92, 1984.\
- Williams, J.A., Presbury, G., Orenstein, D., Dahl, G., Wang, W., Dugdale, M.: Hemothorax and Hemomediastinum in Patients with Hemophilia. Acta. Haemat. 73:176-178, 1985.
- Jason, J., Holman, R.C., Dixon, G., et. al., and The Hemophilia/AIDS Collaborative Study Group: Effects of Exposure to Factor Concentrates Containing Donations from Identified AIDS Patients. J. Amer. Med. Assn. 256:1758-1762, 1986.
- Canale, S.T., Dugdale, M., and Howard, B.C.: Synovectomy of the Knee in Young Patients with Hemophilia. Southern Medical Journal, 81(12):1480-1486, 1988
- Dugdale, M., Britt, Louis G., Vera, S.R., et at.: Identification of the nature of hemostatic failure during transplantation of the liver. Transplantation Proceedings, Vol 21, No. 1, 1989, 2332-2333.
- Hughes, W.T., Kennedy, W., Dugdale, M., Land, M.A., Stein, D.S., et. al: Prevention of Pneumocystis carinii pneumonitis in AIDS patients with weekly dapsone. Lancet. 1066, October 27, 1990
- Deitcher SR, Tuller J, and Dugdale M.: Effect of intermediate- and high-purity factor VIII concentrates on immune function in HIV seropositive hemophiliacs as assessed by quantitative CD4 count. Haemophila (in press).
- Deitcher S, Johnson J, Tuller J, Cholera S, Crawford D, and Dugdale M.: Intranasal DDAVP induced increases in plasma von Willebrand factor (vWf) alter the pharmacokinetics of high-purity factor VIII (FVIII) concentrates in severe hemophilia A patients. Haemophilia 2 (Supplement 1), 13, 1996.
- Guo Z, Zheng X, Thompson W, Dugdale M, and Gollamudi: New carbamoylpiperidiiines as human plaelet aggregation inhibitors. Bioorganic & Medicinal Chemistry 8 (2000) 1041-1058.
- Sallah, S, Dugdale, M., Chesney, C, Wan, I. And Roberts, R.: Inhibitors against factor VIII in patients with underlying malignancy: a clinicopathologic study. Haemophilia (2000), 6, 279-314.
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