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Patricia Ella Adams-Graves, M.D.
Position
Associate Professor of Medicine
Education / Training
- Tennessee State University (Nashville, TN) - BS, Medical Technology; 1970 - 1974
- Meharry Medical College (Nashville, TN) - Medical Technology Externship; 1973 - 1974
- University of Louisville (Louisville, KY) - M.D.; 1982-1986
- Univeristy of Louisville (Humana University Hospital & Affiliates) - Internal Medicine Residency; 1986 - 1989
- University of Tennessee, Memphis - Hematology/Oncology Fellowship; 1990 - 1993
Professional Positions
- University of Tennessee, Memphis - Associate Professor, Division of General Internal Medicine; 2002 - present
- Diggs-Kraus Sickle Cell Center - Directory; 1995 - present
- University of Tennessee, Memphis - Assistant Professor, Division of Hematology/Oncology; 1993 - present
- University of Tennessee, Memphis - Instructor, College of Medicine; 1989-1990
- William F. Bowld Hospital, Regional Medical Center at Memphis, Baptist Memorial Hospital, VAMC - Active Staff
Honors
- Excellence in Clinical Education Award - University of Louisville
- Foreign Language Honor Society (German) - Tennessee State University
- Post Doctoral Research Associate - St. Jude Children's Research Hospital
- Certificate of Special Congressional Recognition for Meritorious Achievement - "In Their Shoes" Harold Ford Jr. (Nominated by A High School Student Who Participated in UT Special Summer Program at Diggs-Kraus Sickle Cell Center); Feb 13, 1999
- "Woman of Excellence". Business & Professional Women's Federation (BPWF) of Gethsemane Garden Institutional Church of God in Christ. Memphis, TN; October 6, 2002
Relevant Publications
- Adams-Graves P., Heltsley C., and Deitcher S.: Ltr. to ed: Hydroxyurea in sickle cell disease. NEJM. 334:333, 1996.
- Adams-Graves P., Kedar A., Koshy M., SteinbergM., Veith R., and Ward D.: RheothRx (Poloxamer 188) Injection For the Acute Painful Episode of Sickle Cell Disease: A Pilot Study; Blood Sept 1, 1997.
- Kennedy C L., Williams-Cleaves B, Adams-Graves P, Connellly J, Wan J; Utilizing Video to Teach Intercultural Medicine in the Clinical Encounter, The Annuals of Behavioral Science and Medical Education: submitted
- Kennedy, C.l., Adams-Graves, P E., Williams-Cleaves, B.J. Video: Intercultural Medicine; 1998.
- Adams-Graves P., Approach To Anemia. Obstetrics and Gynecology: Principles for Practice, Chap. 33, McGraw-Hill, 2000.
- Adams-Graves, P., Blackall, D., Wang, W.; Sickle Cell Anemia: New Hopes / New Treatment, Grace Magazine, Dec. 1998.
- Sinquefield, S., Haman, G., Manno, S., Adams-Graves, P; Effect of Patient Education On Pain Management In Sickle Cell Patients, Thirtieth Annual Southeastern Residency Conference April 29, 1999.
- Adams-Graves P, "Approach To Anemia" Appleton and Lange: Obstetrics and Gynecology: Principles for Practice Short Version Chapter 33
- Adams-Graves P., The Clinical Approach To Anemia in Pregnancy. Contemporary Clinical Gynecology and Obstetrics Journal, Parthenon Publishing, pgs. 1-14, September 2001.
- Orringer EP, Casella JF, Ataga KI, Koshy M, Adams-Graves P; Purified Poloxamer 188 for Treatment of acute Vaso-occlusive Crisis of Sickle Cell Disease. JAMA, Vol 286 No.17:2099, November 7, 2001.
Abstracts (Presented and Published)
- Sandoval C., Adams-Graves P., Parganas E., Wang W, Ihle J.N.: The cytoplasmic portion of the G-CSF receptor is normal in patients with kostmann syndrome. Blood. 82:189a, 1993.
- Adams-Graves P., Phillips C., Mauer A., et al: Development of quality of life instrument for adults with sickle cell disease. The National Sickle Cell Disease Program. 19th Annual Meeting, May 22-25, 1993.
- Adams-Graves P., Kedar A., Koshy M., Steinberg M., Veith R., and Ward D.: RheothRx (poloxamer 88) injection for the acute painful episode of sickle cell disease (scd): A pilot study. Blood. 84:1694, 1994.
- Adams-Graves P., Heltsley C., and Deitcher S.: Melanonychia: An undesirable development during the use of hydroxyurea in adults with sickle cell disease, 21st Annual National Sickle Cell Program, 112, March 6-9, 1996.
- Adams-Graves P, Norfleet L.F, Development of a smoking cessation program for adult cancer patients. Program/Proceedings of the American Society of Clinical Oncology, accepted, 1996.
- Emanuele M, Adams-Graves P, Kedar A, Koshy M, Steinberg M, Veith R, Ward D, RheothRx (Poloxamer 188) Lowers serum LDH during an acute painful episode of Sickle. Blood Vol. 88, No 10 Supplement 1 Nov 15, 1996 .
- M. Koshy, M. Askin, L. McMahon, H. Tamary, P. Adams-Graves, et al, Arginine butyrate in sickle cell leg ulcers: interim findings of a randomized phase II trial. Program/proceedings of the National Sickle Cell Disease Program, 25th Annual Meeting, April 13-17, 2000.
- Jeng M, Adams-Graves P, et al., The effect of erythrocytapheresis on the viscoelasticity of whole blood in sickle cell disease. National Sickle Cell Disease Program, 26th Annual Meeting, April 13-17, 2001.
- Koshy M, Askin M, McMahon L, Tamary H, Adams-Graves P, et al, Arginine butyrate in sickle cell leg ulcers: interim findings of a randomized phase II trial. National Sickle Cell Disease Program, 26th Annual Meeting, April 13-17, 2001
Other
- Adams-Graves P., Jackson A.L., Brooks A. Stop smoking with spiritual power. - This is a training manual to be used for a smoking cessation program in the Memphis area; January 24, 1994.
- Developed a cancer prevention program at Van Vleet Cancer Center Smoking Cessation Initiative in collaboration with University of Memphis, Bob Klesges, Co-director of the UT Prevention Center for general cancer prevention; 1996-97.
- Education Video: Intercultural Medicine, "For Teaching Medical Students Intercultural Communication Skills", Script writer, technical assistant.
Research Support
- Participant Cooperative Study of Sickle Cell Disease - NIH
- Post Doctoral Research Fellow Molecular Biology (St. Jude Children's Research Hospital, Memphis, Tennessee) - "The Cytoplasmic Portion of the G-CSF Receptor is Normal in Patients with Kostmann Syndrome"; 1992 - 1993
- "Smoking Cessation for African Americans with Cancer: A New Beginning". 2/1/95 - 9/1/00 (Linda Norfleet, PI)
- Education Video: "Intercultural Medicine"
- "Development of Quality of Life Instrument for Adults with Sickle Cell Disease". A Multicenter Project on-going. Pilot completed, on-going. (Dr. Adams-Graves, PI)
- "Measuring Bound Hemoglobin In Patients With Hemoglobin Variants". Collaboration with Memphis Pathology laboratory and Dept of Pathology UT; Dr. Smalley, Dr. Paula Herring, Pat Adams-Graves. Ongoing.
- "Intercultural Medicine Cross-Cultural Communications". Kennedy C, Adams-Graves, P, Williams-Cleaves B. 1997-1998 (Dr. Charlotte Kennedy, PI)
- "The Natural History of Strokes in Patients with Sickle Cell Anemia - Retrospective Analysis of Blood Transfusions". 2/2/00 - open (Dr. Adams Graves, PI)
- Post-Transfusion Hemoglobin and Viscoelasticity in Sickle Cell Disease. 6/7/00 - open (Dr. Adams-Graves, PI)
- Multi-site Pilot Study of the Transition of Adolescence and Young Adults with Sickle Cell Disease.
1999 - open (Dr. Adams-Graves, PI)
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled Pilot Study of the Safety and Efficacy of RheothRx (Poloxamer 188) Injection in Patients with Sickle Cell Disease in Active Vaso-Occlusive Disease; 8/1/92 - 12/1/93
- Regional Medical Center at Memphis Blood Transfusion Program: Antigen Typing for Sickle Cell Patients Diggs-Kraus Sickle Cell Center and United Way of the MidSouth; 6/95 - open
- A Dose Ranging Study of the Efficacy and Tolerability of Multiple doses of Cordox (FDP) as Adjunct Therapy in the Management of An Acute, Sickle Cell Related, Painful, Vaso-occlusive Episode; 10/07/98 - 6/1/00
- Quit to Live Nicotine Replacement Smoking Cessation for Minorities in Memphis; 2/1/95 to 9/1/99
- Phase I Study of CRL 5861 (Purified Poloxamer 188) in Patients with Sickle Cell Disease in Acute Vaso-Occlusive Crisis; 3/17/97 - 3/19/2001
- A Phase III Multicenter Randomized Double Blind Placebo Controlled Study of Flocor in Patients with Sickle Cell Disease in Vasooclusive Crisis; 7/16/97 - 10/11/99
- A Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Intravenous Ondansetron HCL in The Treatment of Opioid-Induced Nausea and Emesisi in Subjects Experiencing An Acute Sickle Cell Disease Pain Episode (Sickle Cell Crisis); 4/7/94 - 5/7/95
- Phase II Trial of Arginine Butyrate for Treatment of Refractory Leg Ulcers in Patients with Sickle Cell Disease or Beta Thalassemia; 7/1/94 - open
- Phase II Open Label Safety Study of Repeated Administration of Flocor in Patient with Sickle Cell Disease in Vasooclusive Crisis; 2/3/99 - 1/9/01
- United Way Agency: Diggs-Kraus Adult Sickle Cell Program. Social Service Program Development; 6/1/95 - open
- Delta Foundation: Diggs-Kraus Adult Sickle Cell Program. Leg Ulcer Program; 2000 - open
- Evaluation of the Recovery of all transduction, Efficiency and Phenotypic Consequences of Genetic Modification of Primitive Hematopoietic Cells from Patients with Sickle cell disease; 1999 - open
- A Phase II, Multicenter, Twelve-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Range-Finding Study of the Efficacy and Safety of ICA-17043 with or without Hyroxyurea Therapy in Patients with Sickle Cell Anemia. (Pending IRB approval); 1/06/02 - open
Committees and Task Forces
- Institutional Review Board, 2000 - present
- NIH, Data and Safety Monitoring Board (DSMB), Multicenter Study of Hydroxyurea (MSH) - Patients' FollowUp; 1996 - 2001
- TLC Chronic / Catastrophic / Specialty Care Subcommittee; 1997-2000
- American Cancer Society Task Force member (Great American Smoke-out); 1992-1994
- American Cancer Answer Week Committee; 1992-1996
- Medicine Service Patient Care Committee - Regional Medical Center; 1989 - 1990
- Psychosocial Interest Group - National Sickle Cell Diseae Program Coping Committee; 1991 - 1996
- PAAST (Preventing African-American Stroke Due to Tobacco Use) Medical Advisor; 1989-Present
- MBCC(Mississippi Boulevard Counseling Center) Support Group Leader for WATSA(Wholistic Approach to Substance Abuse); 1989-1991
- MBCC(Mississippi Boulevard Counseling Center) Support Group Leader for Sexually Assaulted Victims; 1993
- MBCC(Mississippi Boulevard Counseling Center) Project Achieve (Minority high schoolers interested in Science) - Mentor; 1989-Present
- Cessation PAAST, Inc., Director/Medical Advisor for Health Promotion, Prevention, Training Program for Smoking, 6 week training period
- PAAST, Executive Chair; 1994
- HCOP, Advisory Council; 1994-1996
- University of Tennessee - Oral Cancer Research Committee; 1995-1996
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