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Division Faculty

Lester VanMiddlesworth, Ph.D., M. D.
Professor Physiology and Medicine, UTHSC

University Distinguished Professor, presented 2007



M.S. Chemistry, Univ. Virginia, 1942
Ph.D. Physiology, University California, Berkeley, 1946
M.D. Univ. Tenn. Health Science Center, 1951

Interests:
Basic and clinical thyroid-physiology
Natural and unnatural radioactivity in the thyroid
Diagnosis and treatment of thyroid disease
Thyroid function in pregnancy

Publications = 152.
Three current publications:

Brozyna Anna A., VanMiddlesworth Lester, Slominski Andrzej T. Inhibition of melanogenesis as a method of sensitizing human melanoma cells to gamma radiation Running title: Melanin attenuates radiosensitivity of melanoma. In review Pathology Journal.

Khurana S., George S, Mathew S, Siddiqui M, Srinivasan K, Tan L, Wang, L, Vanmiddlesworth, L. Reorganization of cytoskeleton as basis for apoptosis. In preparation.

VanMiddlesworth L, VanMiddlesworth NR, Egerman RL, Ho Eugene, Bush AJ, Ramsey R, Delmar, LP, Wu SY. Thyroid Function and Compound W in Maternal Hyperthyroidism Treated with Antithyroid Medication. In review by THYROID.


Current Research:

  1. Cell biology: A) Effect of gamma radiation of cultured rat thyroid cells. B) Effect of antithyroid drugs on gamma radiated cultured rat thyroid cells. Supported by a UTMG grant.

  2. Detection of radioiodine fallout (129I) in thyroids of deer around nuclear reprocessing areas. Supported by Westinghouse Savannah River Project.