Faculty

Murray Heimberg, Ph.D., M.D.
Distinguished Professor of

Pharmacology and Medicine, Emeritus
Room 100 Crowe Research Building
(901) 448-4748
FAX (901) 448-7200
mheimberg@utmem.edu

Education:
Cornell University, Ithaca, NY, B.S, 1948, Bacteriology
Cornell University, Ithaca, NY, M.N.S., 1949, Nutrition
Duke University, Durham, NC, Ph.D., 1952, Biochemistry
Vanderbilt University, Nashville, TN, M.D., 1959, Medicine

Washington University, St. Louis, MO, 1952-54; Postdoctoral Fellow (Biochemistry)

Clinic Locations:

Germantown
7945 Wolf River Boulevard, Suite 120
Germantown, Tennessee 38138-1733
901-448-4801, Fax: 901-448-8192

Memphis Medical Center

1365 Eastmoreland Avenue, Suite 365
Memphis, Tennessee, 38104-7514
901-448-4801, Fax: 901-448-7296

Academic Title: University Distinguished Professor of Pharmacology and Medicine, Emeritus, University of Tennessee Center for Health Sciences.

Clinical Interests:

Lipid Metabolism and Cardiovascular Disease

Diabetes and General Endocrinology

Professional Memberships:

American Association for the Advancement of Science, Fellow
American Diabetes Association
American Heart Association, Council on Arteriosclerosis, Fellow
American Oil Chemists Society
American Society of Biochemistry and Molecular Biology
American Society for Pharmacology and Experimental Therapeutics
American Society for the Study of Liver Diseases
Sigma Xi, Scientific Honor Society
Southern Society for Clinical Investigation

The Endocrine Society

Awards & Honors:

Lederle Medical Faculty Award
Established Investigator, American Heart Association
Listed in

   Who's Who in America

   Who's Who in the South and Southwest

   American Men and Women of Science

   Who's Who in Science and Engineering

   Who's Who in American Education

   Guide to America's Top Physicians

Research Interests:
Metabolic regulation and endocrine pharmacology

Serum lipids-lipoproteins and atherosclerosis

Hepatic function, drug metabolism, and hepatotoxicity

Selected Publications:
Regulation of Hepatic secretion of the very low density lipoprotein by dietary cholesterol. T.V. Fungwe, L. Cagen, H.G. Wilcox, and M. Heimberg. J. Lipid Research, 33, 179-191 (1992).

Concentration-dependent effects of eicosapentaenoic and on VLDL secretion by the isolated perfused rat liver. Z.J. Zhang, H.G. Wilcox, L. Castellani, T.V. Fungwe, M.B. Elam, and M. Heimberg. Lipids 28, 419-425 (1993).

Dietary cholesterol stimulates hepatic biosynthesis of triglyceride and reduces oxidation of fatty acids in the rat. T.V. Fungwe, L.M. Cagen, G.A. Cook, H.G. Wilcox, and M. Heimberg. J. Lipid Res. 34, 933-941 (1993).

Stimulation of fatty acid biosynthesis by dietary cholesterol and of cholesterol synthesis by dietary fatty acid. T.V. Fungwe, J. Fox, L.M. Cagen, H.G. Wilcox, and M. Heimberg. J. Lipid Res.35:311-318 (1994).

Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by altering apolipoprotein B mRNA editing. F.E. Thorngate, R. Raghow, H.G. Wilcox, C.S. Werner, M. Heimberg, and M.B. Elam. Proc. Natl. Acad. Sci., USA, 91:5392-5396, 1994.

Altered hepatic catabolism of low density lipoprotein subjected to in vitro lipid peroxidation. W.L. Stone, M. Heimberg, R.L. Scott, I. LeClair, and H. G. Wilcox. Biochem J. 297:5734-579 (1994).

Fungwe TV, Fox JE, Cagen LM, Wilcox HG, Heimberg M . Stimulation of fatty acid biosynthesis by dietary cholesterol and of cholesterol synthesis by dietary fatty acid. J Lipid Res 35(2):311-8, 1994

Stone WL, Heimberg M, Scott RL, LeClair I, Wilcox HG . Altered hepatic catabolism of low-density lipoprotein subjected to lipid peroxidation in vitro. Biochem J 297 ( Pt 3):573-9, 1994

Fungwe TV, Cagen LM, Wilcox HG, Heimberg M . Effects of dietary cholesterol on hepatic metabolism of free fatty acid and secretion of VLDL in the hamster. Biochem Biophys Res Commun May 200(3):1505-11, 1994.

Thorngate FE, Raghow R, Wilcox HG, Werner CS, Heimberg M, Elam MB . Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by altering apolipoprotein B mRNA editing. Proc Natl Acad Sci U S A 91(12):5392-6, 1994.

Hughes TA, Heimberg M, Wang X, Wilcox H, Hughes SM, Tolley EA, Desiderio DM, Dalton JT. Comparative lipoprotein metabolism of myristate, palmitate, and
stearate in normolipidemic men. Metabolism 45(9):1108-18, 1996.

Elam MB, Cushman W, Applegate WB, Heimberg M. Recent developments in coronary heart disease prevention: the and west of Scotland studies. Tenn Med May;90(5):189-9, 1997.

von Wronski MA, Hirano KI, Cagen LM, Wilcox HG, Raghow R, Thorngate FE, Heimberg M, Davidson NO, Elam MB. Insulin increases expression of apobec-1, the catalytic subunit of the apolipoprotein B mRNA editing complex in rat hepatocytes. Metabolism 47(7):869-73, 1998.