I.      Regulations, Legislation and Training Needs Relevant to the Use of Animals in Research
    A.      Laws and regulations
    B.      Alternatives to the use of animals in biomedical research
    C.      Responsibilities
        1.      Animal care technicians
        2.      Research technicians, graduate students, and postdoctoral fellows
        3.      Principal investigators
        4.      How to report animal misuse or grievances
    D.      Training Policy
        1.      USDA and PHS training mandates
        2.      Animal care staff: AALAS certification training
        3.      Research staff: Academy of Surgical Research technician training
        4.      Graduate courses: Essentials of Animal Experimentation and 
                The Biology and Pathophysiology of Laboratory Animals           
        5.      DCM library (partial list of holdings)

II.     Institutional Animal Care and Use Committee (IACUC)
    A.      Procedures for submission and approval of animal use protocols.
    B.      IACUC guidelines for the use of animals.
    C.      Sample IACUC protocol form
    D.      Pain and Distress categories
    E.      Sample IACUC Protocol Revision form

III.    Department of Comparative Medicine (DCM)
    A.      Who to contact
    B.      Departmental policies
        1.      Ordering procedures
            a.      Animals
            b.      Drugs
        2.      Services offered
            a.      Research consultation
            b.      Technical help
            c.      Laboratory services
            d.      Room reservations
            e.      Animal transportation
        3.      Veterinary care and diagnostic services 
    C.      Animal care and use
        1.      Facilities overview
            a.      Coleman Building 
            b.      Nash Building
            c.      Molecular Sciences Building
            d.      Wittenborg Building
        2.      DCM animal technician responsibilities
        3.      Animal environment
            a.      Macro-environment
            b.      Micro-environment
            c.      Enrichment
        4.      Rodent holding areas
            a.      Quarantine
            b.      Open barrier
            c.      Closed barrier
            d.      Biohazard containment
        5.      Animal husbandry equipment (cages, water bottles, food, etc.)
            a.      What to do with dirty equipment
            b.      Where to get clean equipment
            c.      Other assistance
        6.      Animal Death Notice Information 

IV.     Experimental Techniques in Animal Research
    A.      Guide to anesthesia, analgesia, and tranquilization
    B.      Surgery - essential considerations
    C.      Euthanasia

V.      Occupational Health, Safety, and Biohazards
    A.      Occupational health
    B.      Hazards associated with animals
    C.      Personal hygiene
    D.      Safety related to sanitation
    E.      General safety rules
    F.      Projects using biohazards
    G.      Response to injuries 
    H.      Zoonoses associated with laboratory animals
        1.      General considerations
        2.      Category 1 or 2 exposure
        3.      Category 3 exposure
        4.      Category 4 exposure
        5.      Special considerations
    I.      Conclusions
    J.      References

VI.     Appendices
    A.      Surgical information
        1.      Types of surgical procedures and appropriate facilities
        2.      Preoperative planning
        3.      Sterile technique
        4.      Instrument use and tissue handling
        5.      Surgical techniques
        6.      Suture materials
        7.      Intraoperative and postoperative care
        8.      References
    B.      Species information

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