| Publications :: | Associate
Professor of Pediatrics Division of Pediatric Nephrology 
Elevated blood pressure has a major impact upon the health of the
heart and the kidneys. Children may have elevated blood pressure as
a result of kidney disease or may have the beginning of adult high
blood pressure in childhood. The exact level of blood pressure at
which one can anticipate damage to kidneys and heart muscle is not
as clearly defined in children as it has been in adults. This is important
because it will guide treatment of children with elevated blood pressure.
Dr. Deborah Jones’ research funded by the CFRC is aimed at defining
changes in the thickness of the heart muscle and increases in urinary
protein, plus kidney function, in relation to measurement of blood
pressure over 24 hours. Preliminary results from the study show that
mean ambulatory blood pressure significantly correlates with measures
of left heart size and kidney function in a group of children with
mild hypertension. Dr. Jones’ results have important implications
for the early diagnosis and treatment of children with elevated blood
pressure to prevent associated heart and kidney disease later in life. |
Lau KK, Ault BH, Jones DP. Polymicrobial peritonitis including Pantoea agglomerans from teething on a catheter. South Med J 2005; 98(5):580-581 Lau KK, Weiss AR, Jones DP. Polyuria associated with high-dose methotrexate in two patients with acute lymphoblastic leukemia. J Oncol Pharm Practice 2005; 11:31-33 Hale GA, Bowman LC, Rochester RJ, Benaim E, Heslop HE, Krance RA, Horwitz E, Cunningham JM, Tong X, Srivastava DK, Handgretinger R, Jones DP. Bone marrow transplant associated hemolytic uremic syndrome: clinical characteristics and outcome. Biol Blood Marrow Transplant 2005; 11:912-910 Lau KK, Jones DP, Hastings MC, Gaber LW, Ault BH. Short-term outcomes of severe lupus nephritis in a cohort of predominantly African-American children. Pediatr Nephrol 2006; 21: 655-662 Han X, Patters AB, Jones DP, Zelikovic I, Chesney RW. The taurine transporter: mechanisms of regulation. Acta Physiol 2006; 187:61-73 McGlothan KR, Wyatt RJ, Ault BH, Hastings MC, Rogers T, DiSessa T, Jones DP. Predominance of nocturnal hypertension in pediatric renal transplant recipients. Pediatr Transplant 2006; 10:558-564 Hastings MC, Wyatt RJ, Jones DP, Lau KK, Powell SL, Hayes DW, Gaber LW, Gaber AO, Ault BH. Five years' experience with Thymoglobulin induction in a pediatric renal transplant population. Pediatr Transplant 2006; 10(7):805-810. Bashir H, Crom DB, Jones DP, Hudson M. Cisplatin-induced hypomagnesemia and cardiac dysrhythmia. Pediatr Blood and Cancer, 2006; [Epub ahead of print] PMID: 16619211 |