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| Publications
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Associate
Professor of Pediatrics
Division Chief, Pediatric Cardiology
Dr. Thomas Chins research interests are in the field of cardiac
physiology, with a special interest in altered contractility at the
ventricular myocyte (heart muscle cell) level during development,
and with congenital heart disease. Current studies, performed in collaboration
with the Molecular Cardiology Laboratory at the NIH/NHLBI, focus on
altered myocyte structure and function in a mouse model with the congenital
heart defect Tetralogy of Fallot, an important problem in children.
Dr. Chin has additional research interests in cardiomyopathies and
the treatment of hypercholesterolemia in children and adolescents.
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Chin TK,
Christiansen GA, Caldwell JG, Thorburn J: Contribution of the sodium-calcium
exchanger to contractions in imma-ture rabbit ventricular myocytes.
Pediatr Res 41:480-85, 1997.
Bleyl SB, Mumford BR, Brown-Harrison MC, Pagotto LT, Carey JC, Pysher
TJ, Ward K, Chin TK: Xq28-linked non-compaction of the left
ventricular myocardium (INVM): Prenatal diagnosis and pathologic analysis
of affected individuals. AJMG 72:257-65, 1997.
Bleyl SB, Mumford BR, Thompson V, Carey JC, Pysher TJ, Chin TK,
Ward K: Neonatal lethal non-compaction of the left ventricu-lar myocardium
is allelic to Barth Syndrome. AJHG 61:868-72, 1997.
Kao RL, Davis J, Chin TK, Ganote CE, Hossler FE, Li C, Browder
W: Satellite cell transplan-tation to repair injured myocardium. Cardiac
& Vasc Regeneration 1:31-342, 2000.
Stone, WL, Chin TK: The use of genetically altered mice in
studying atherosclerosis. Curr Opin in Cardiovasc, Pulm, Renal Inves
Drugs 2 (3):250-57, 2000.
Takeda K, Yu ZX, Qian S, Chin TK, Adelstein RS, Ferrans VJ:
Nonmuscle myosin II localizes to the Z-lines of skeletal muscle. Cell
Motil. Cytoskeleton 46:59-68, 2000.
Stone WL, Chin TK: Drugs for the treatment of hyperlipidemia.
Curr Opin in Cardiovasc, Pulm, Renal Invest Drugs 2001 (in press).
Pershad J, Chin TK: Early detection of cardiac disease masquerading
as acute bronchospasm: The role of bedside limited echocardiography
by the emergency physician. Peds Emerg Care (in press). |
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