HYPERTENSION /CARDIOLOGY ::    THOMAS CHIN, M.D.      tchin@utmem.edu  
 
 Publications :: Associate Professor of Pediatrics
Division Chief, Pediatric Cardiology


Dr. Thomas Chin’s research interests are in the field of cardiac physiology, with a special interest in altered contractility at the ventricular myocyte (heart muscle cell) level during development, and with congenital heart disease. Current studies, performed in collaboration with the Molecular Cardiology Laboratory at the NIH/NHLBI, focus on altered myocyte structure and function in a mouse model with the congenital heart defect Tetralogy of Fallot, an important problem in children. Dr. Chin has additional research interests in cardiomyopathies and the treatment of hypercholesterolemia in children and adolescents.
Chin TK, Christiansen GA, Caldwell JG, Thorburn J: Contribution of the sodium-calcium exchanger to contractions in imma-ture rabbit ventricular myocytes. Pediatr Res 41:480-85, 1997.

Bleyl SB, Mumford BR, Brown-Harrison MC, Pagotto LT, Carey JC, Pysher TJ, Ward K, Chin TK: Xq28-linked non-compaction of the left ventricular myocardium (INVM): Prenatal diagnosis and pathologic analysis of affected individuals. AJMG 72:257-65, 1997.

Bleyl SB, Mumford BR, Thompson V, Carey JC, Pysher TJ, Chin TK, Ward K: Neonatal lethal non-compaction of the left ventricu-lar myocardium is allelic to Barth Syndrome. AJHG 61:868-72, 1997.

Kao RL, Davis J, Chin TK, Ganote CE, Hossler FE, Li C, Browder W: Satellite cell transplan-tation to repair injured myocardium. Cardiac & Vasc Regeneration 1:31-342, 2000.

Stone, WL, Chin TK: The use of genetically altered mice in studying atherosclerosis. Curr Opin in Cardiovasc, Pulm, Renal Inves Drugs 2 (3):250-57, 2000.

Takeda K, Yu ZX, Qian S, Chin TK, Adelstein RS, Ferrans VJ: Nonmuscle myosin II localizes to the Z-lines of skeletal muscle. Cell Motil. Cytoskeleton 46:59-68, 2000.

Stone WL, Chin TK: Drugs for the treatment of hyperlipidemia. Curr Opin in Cardiovasc, Pulm, Renal Invest Drugs 2001 (in press).

Pershad J, Chin TK: Early detection of cardiac disease masquerading as acute bronchospasm: The role of bedside limited echocardiography by the emergency physician. Peds Emerg Care (in press).
 
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