Investigator Awards
Since 1995, CFRC investigators have received over $16 million in total NIH and other federal grants and $14 million in non-federal support. Over the past three years, CFRC investigators have significantly increased extramural funding. Since 2001, annual total (direct plus indirect) NIH funding has increased from $1,249,989 to $3,173,286 for 2004, and CFRC investigators currently hold active grants totaling over $13 million (direct plus indirect) for 3 to 5 year funding periods.
| Principal Investigator | Sponsor | Project Title | Award Amount |
|---|---|---|---|
| Ronald Adkins | NSF | Muroid Rodent Phylogenetics Using Multiple Nuclear Genes |
$189,895
|
| CFRC | Molecular Genetic Analysis of Birthweight Variation |
$50,000
|
|
| Gail Beeman | CFRC/LHS, Inc | Health Promotion for Hispanic Children: Obesity Prevention |
$322,653
|
| Dennis D. Black | NIH | Intestinal Lipoproteins in the Neonate |
$1,447,875
|
| CFRC | CFRC Director’s Fund |
$2,500,000
|
|
| George Burghen | NIH | The Diabetes Prevention Trial-Type 1 |
$80,000
|
| Industry | Diabetes Treatment Study |
$58,000
|
|
| Industry | Diabetes Treatment Study |
$161,258
|
|
| Industry | Diabetes Treatment Study |
$66,000
|
|
| CFRC/LHS, Inc. | Intervention
Study of Obese African-American Children |
$80,000
|
|
| Pedro Velasquez-Mieyer | CFRC | Race,
Obesity and Enteroinsular Axis In Adolescents |
$150,000
|
| Industry | Obesity Treatment Study |
$50,000
|
|
| Industry | Obesity Treatment Study |
$140,000
|
|
| Industry | Diabetes Treatment Study |
$120,500
|
|
| Bruce Alpert | NIH | Genetics of Cardiovascular Reactivity in Black Youth |
$2,376,320
|
| Noel Delos-Santos | NIH | Role of C-IV in -1 AR Coupling to G protein |
$113,024
|
| LBCMC | The Endocytic Scaffold of the Human -1 Adrenergic Receptor |
$13,000
|
|
| Deborah Jones | CFRC/LHS,Inc. | Ambulatory Blood Pressure Patterns and End-Organ Damage in Children |
$181,697
|
| LBCMC | Bone Mineral Density in Children with Hypercalciuria |
$10,000
|
|
| Russell Chesney | NIH | Pediatric Pharmacology and Pharmacokinetics |
$3,289,749
|
| NIH | Renal b-Amino Acid Transport and Altered Dietary Intake Research Grant |
$1,843,160
|
|
| NIH | Differences in mRNA Using a Known cDNA Probe of NaC1-Dependent Taurine Transport Isolated From MDCK Renal Cells |
$168,980
|
|
| NIH | Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency-Genetic Basis for Azathioprine Intolerance In Children with Immunosuppressive Therapy |
$491,434
|
|
| Michael Christensen | Industry | Parenteral Nutrition |
$67,800
|
| Industry | Adolescent Migraine Treatment Study |
$15,750
|
|
| Industry | Pediatric Pharmacology Study |
$16,800
|
|
| Industry | Pediatric Pharmacology Study |
$12,000
|
|
| Industry | Adolescent Migraine Treatment Study |
$72,312
|
|
| LBCMC | Pediatric Asthma Treatment Study |
$9,750
|
|
| Industry | Pediatric Diabetes Treatment Study |
$350,000
|
|
| Xiaobin Han | CFRC | Renal Taurine Transporter Gene in Kidney |
$30,000
|
| LBCMC | Differential Regulation of Taurine Transporter Gene by Estrogen Receptors |
$10,000
|
|
| LBCMC | Regulation of the Taurine Transporter Gene |
$5,000
|
|
| David Rogers | NIH | Novel Azole Resistance Mechanisms in C. albicans |
$292,000
|
| Bettina Ault | CFRC | Complement
Gene Expression in the Developing Kidney And Effect of Acute Phase Stimuli and Obstruction |
$57,386
|
| CFRC | The Role of Complement in the Pathogenesis of Hemolytic Uremic Syndrome |
$33,794
|
|
| Nat. Kidney Foundation | Complement Factor H in Patients with Idiopathic Hemolytic-Uremic Syndrome |
$5,000
|
|
| LBCMC | Complement in Shiga Toxin-Mediated Endothelial Injury |
$7,000
|
|
| Edsel Arce-Hernandez | CFRC | Phenotypic and Functional Alterations of the Peripheral Blood B Cell Compartment in Pediatric Systemic Lupus Erythematosis |
$50,000
|
| John DeVincenzo | NIH | Immunogenetics and the Pathogenesis of RSV Infection |
$580,215
|
| Industry | RSV Study in Infants |
$416,000 |
|
| Industry | RSV Study in Premature Infants |
$45,888
|
|
| CFRC | Investigations into Potential Strategies for the Treatment of RSV Infections |
$68,394
|
|
| CFRC | The
Pathogenesis of RSV Infections Interactions
of Immunogenetics, Viral Load, and Disease Severity |
$42,590
|
|
| Industry | RSV Treatment Study |
$25,000
|
|
| Industry | RSV Treatment Study |
$36,250
|
|
| Keith English | Industry | S. aureus Treatment Study |
$22,500
|
| NIH | Role of HCK in Myeloid Differentiation and Activation |
$402,912
|
|
| American Heart Association | SHP-1
Tyrosine Phosphatase Regulates Macrophage Activation |
$120,000
|
|
| D. Betty Lew | Industry | Pediatric Drug Study |
$122,400
|
| Industry | Mouse Model of Asthma |
$20,000
|
|
| Industry | Pediatric Allergy and Immunology |
$150,000
|
|
| NIH | Airway
Myocyte Proliferation and Lysosomal Hydrolases |
$1,010,376
|
|
|
CFRC |
Airway Myocyte Proliferation and Lysosomal Hydrolases |
$139,136
|
|
| Industry | Pediatric Asthma, Allergy and Immunology |
$33,667
|
|
| Linda Myers | NIH | Analog Peptides in Collagen-Induced Arthritis |
$1,622,691
|
| Arthritis Foundation | Antigen-Specific Suppression of Collegen-Induced Arthritis Immunogenic Determinants |
$315,332
|
|
| NIH | Immunogenic Epitopes of Collagen Critical in Arthritis |
$350,000
|
|
| Arthritis Foundation | Altered Peptide Ligands in Collagen Arthritis |
$166,666
|
|
| Michael Quasney | NIH | Genetic Polymorphisms in Pediatric Lung Injury |
$401,500 |
| CFRC | Functional Domains of theHuman D1 Dopamine Receptor |
$110,500
|
|
| American Heart Association | Genetic Polymorphisms in the TNF Locus in Children with Kawasaki Disease |
$118,800
|
|
| Industry | Clinical Study |
$55,000
|
|
| American Lung Association | Impact of TNF and IL-10 Gene Polymorphisms on Outcome in Pneumonia |
$50,000
|
|
| NIH | Gene Polymorphisms in the Prevention of Disability |
$1,627,613
|
|
| Robert J. Wyatt | NIH | Genetics of lgA Nephropathy |
$303,454
|
| Industry | Pediatric Nephropathy Study |
$25,000
|
|
| Ae-Kyung Yi | NIH |
Induction of Immunological Paralysis in CpG DNA |
$1,430,000
|
| CFRC | Immunomodulation by Cpg DNA |
$30,000
|
|
| UTHSC | Protein Kinase C in the CpG DNA-Induced Innate Immunity |
$20,000
|
|
| CFRC | CpG
DNA-mediated Biochemical Signaling Pathways which Lead to Mitogen-Activated Protein Kinase |
$150,000
|
|
| NIH | Role
of PKD in Leukocyte Activation by CpG DNA |
$185,400
|
|
| Leukemia Research Foundation | Elucidation
of Mechanisms by which MEK/ERK Negatively Regulates CpG-DNA–Mediated Th1 Response |
$75,000
|
|
| Arthritis Nat. Research Foundation | CpG-DNA-Mediated
Biochemical Signaling
Pathways which Lead to Mitogen-Activated Protein Kinase |
$50,000
|
|
Arthritis Foundation |
Study
on the Lymphocyte Activation Mediated by Oligodeoxynucleotide-Containing Unmethylated CpG Motifs |
$26,500
|
|
| Lupus Foundation | Study
on the Signaling Pathway through which Immune Stimulatory CpG Motifs in Bacterial DNA May Break B Cell Tolerance |
$15,000
|
|
| UTHSC | Pilot and Feasibility Grant Program |
$40,000
|
|
| Marion Hare |
CFRC/LHS,Inc. |
SPARK
Pre-K: Physical Activity Program For Pre-Schoolers |
$332,828
|
| Karen Lakin | CFRC | Imprinting
Bicycle Helmet Use in Children |
$150,000
|
| DHHS | Safe
and Bright Futures for Children Initiative |
$150,000
|
|
| Marian Levy | CFRC | Pediatric Wellness and Health Promotion |
$100,000
|
| Industry | Cultural Competency Training |
$50,000
|
|
| March of Dimes | Promotion
Prenatal Care for Hispanic Women |
$28,435
|
|
| Robert Wood Johnson Foundation | We Speak Together |
$11,970
|
